איכות עובר נמוכה

בראש ובראשונה העובדה שהרית היא המבורכת,יחד עם זאת הריונות שמקורם ב-TESE עם ICSI כרוכים בשיעור גבוה יותר של הפרעות גנטיות ,לכן יהיה צורך במעקב קפדני ויתכן גם ביצוע של בדיקת מי שפיר עם צ'יפ גנטי,מלבד המעקב המקובל להערכת ההתפתחות והגדילה של העובר-להלן המאמר משנה זו: Int J Fertil Steril. 2014 Apr;8(1):35-42. Epub 2014 Mar 9. Chromosomal abnormality in men with impaired spermatogenesis. Mierla D1, Jardan D2, Stoian V3. Author information 1Life Memorial Hospital, Bucharest, Romania ; Department of Genetics, Faculty of Biology, University of Bucharest, Bucharest, Romania. 2Life Memorial Hospital, Bucharest, Romania. 3Department of Genetics, Faculty of Biology, University of Bucharest, Bucharest, Romania. Abstract BACKGROUND: Chromosomal abnormalities and Y chromosome microdeletions are regarded as two most frequent genetic causes associated with failure of spermatogenesis in the Caucasian population. MATERIALS AND METHODS: To investigate the distribution of genetic defects in the Romanian population with azoospermia or severe oligozoospermia, karyotype analysis by G-banding was carried out in 850 idiopathic infertile men and in 49 fertile men with one or more children. Screening for microdeletions in the azoospermia factor (AZF) region of Y chromosome was performed by multiplex polymerase chain reaction (PCR) on a group of 67 patients with no detectable chromosomal abnormality. The results of the two groups were compared by a two-tailed Fisher's exact test. RESULTS: In our study chromosomal abnormalities were observed in 12.70% and 8.16% of infertile and fertile individuals respectively. CONCLUSION: Our data suggests that infertile men with severe azoospermia have higher incidences of genetic defects than fertile men and also patients from any other group. Infertile men with normal sperm present a higher rate of polymorphic variants. It is important to know whether there is a genetic cause of male infertility before patients are subjected to intracytoplasmic sperm injection (ICSI) or testicular sperm extraction (TESE)/ICSI treatment. KEYWORDS: Azoospermia; Chromosomal Abnormality; Chromosome Microdeletion; Male Infertility; Oligozoospermia

עמדתך ברורה ,יחד עם זאת אין זה אומר שהרופא לא חייב לידע אותך במכלול האפשרויות ולנהל מעקב כנדרש. אשכים אטרופים -מדובר באשכים מנוונים בדרגה כזו או אחרת