טיפול באנסטרזול גיל עצמות מתקדם

1) 8 חודשים בגיל זה זו אינה התקדמות מרשימה, אלא קידום בתחום הנורמה 2) ארימידקס= אנסטראזול אינה תרופה הרשומה לעיכוב גיל עצמות. משתמשים בה כבר מספר שנים למטרה זו כיוון שהיא מעכבת את התקדמות גיל העצמות ובכך נותנת סיכוי לגדילה נוספת. שימושה העיקרי הוא לטיפול בחולי סרטןלעיכוב יציררת ההורמון הנשי, אסטרוגן. זאת מכיוון שהאסטרוגן גם בבנים וגם בבנות מקדם את גיל העצמות. 3) לא תמצאי ספרות על תופעות לוואי בילדים אלא באופן כללי על מבוגרים 4) אם תחזית הגובה הסופי נמוכה, ניתן להשתמש בתרופה לעיכוב גיל העצמות. אין לי שום מידע על בנך האומר לי מה תחזית הגובה הסופי שלו- הרופאה שלו בוודאי חשבה זאת. אני משתמש בתופה זו לפחות 8 שנים ולא ראיתי בעיה מיוחדת תופעות הלוואי הכתובות על תרופה זו הן: Anastrozole (ARIMIDEX) Side Effects In addition to its needed effects, some unwanted effects may be caused by anastrozole. In the event that any of these side effects do occur, they may require medical attention. Major Side Effects You should check with your doctor immediately if any of these side effects occur when taking anastrozole: More common: Blurred vision chest pain or discomfort dizziness headache nervousness pounding in the ears shortness of breath slow or fast heartbeat swelling of the feet or lower legs Less common: Arm, back, or jaw pain chest tightness or heaviness cough or hoarseness difficult or painful urination dizziness, severe fever or chills headache, continuing increased blood pressure lower back or side pain nausea pain, tenderness, bluish color, or swelling of the foot or leg sore throat sudden shortness of breath sweating unusual tiredness or weakness vaginal bleeding (unexpected and heavy) Incidence not known: Blistering, peeling, or loosening of the skin hives itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs red skin lesions, often with a purple center sores, ulcers, or white spots in the mouth or on the lips Minor Side Effects Some of the side effects that can occur with anastrozole may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional: More common: Acid or sour stomach back pain belching body aches or pain bone pain congestion constipation decrease in height diarrhea dry mouth dryness or soreness of the throat feeling of warmth fever flushing or redness of the skin, especially on the face and neck heartburn hot flashes increased appetite indigestion lack or loss of strength loss of appetite mood or mental changes pain in the back, ribs, arms, or legs pain, general pelvic pain runny nose skin rash stomach discomfort, upset, or pain tender, swollen glands in the neck trouble in swallowing voice changes vomiting weakness weight loss Less common: Anxiety and confusion breast pain chills cough producing mucus difficulty breathing dryness of the vagina general feeling of discomfort or illness itching of the skin joint pain and stiffness loss of hair muscle pain numbness or tingling of the hands or feet shivering sleepiness or unusual drowsiness trouble sleeping or sleeplessness weight gain wheezing For Healthcare Professionals Applies to anastrozole: compounding powder, oral tablet Cardiovascular Cardiovascular side effects have included hypertension (up to 13%), edema (up to 11%), including peripheral edema (up to 9%). Ischemic cardiovascular disease (4%) has also been reported.[Ref] Musculoskeletal Very common (10% or more): Arthritis/arthralgia/arthrosis/joint disorder/joint pain/joint stiffness (36%), back pain (12%), bone pain (12%), osteoporosis (11%), fracture (10%) Common (1% to 10%): Myalgia, anorexia Uncommon (0.1% to 1%): Trigger finger[Ref] Gastrointestinal Very common (10% or more): Nausea (20%), vomiting (11%) Common (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, gastrointestinal disorder, dry mouth[Ref] Other Very common (10% or more): Fatigue/asthenia (19%), pain (17%), accidental injury (10%), lymphedema (10%), peripheral edema (10%) Common (1% to 10%): Infection, flu syndrome, cyst, fever, neck pain, malaise[Ref] Psychiatric Very common (10% or more): Mood disturbances (19%), depression, insomnia[Ref] Nervous system Very common (10% or more): Headache (18%), depression (13%), insomnia (10%) Common (1% to 10%): Dizziness, anxiety, paresthesia, hypertonia, cerebrovascular event (cerebrovascular accident, cerebral ischemia, cerebral infarct), somnolence, confusion, nervousness, carpal tunnel syndrome, sensory disturbances (e.g., taste loss and taste perversion)[Ref] Dermatologic Very common (10% or more): Rash (11%) Common (1% to 10%): Sweating, alopecia/hair thinning, pruritus Rare (less than 0.1%): Skin reactions (lesions, ulcers blisters), erythema multiforme, cutaneous vasculitis (including Henoch-Schonlein purpura) Very rare (less than 0.01%): Stevens-Johnson syndrome[Ref] Respiratory Very common (10% or more): Dyspnea (11%), increased cough (11%), pharyngitis (10%) Common (1% to 10%): Sinusitis, bronchitis, rhinitis[Ref] Genitourinary Common (1% to 10%): Urinary tract infection, breast pain, vulvovaginitis, vaginal hemorrhage, vaginitis, vaginal discharge, vaginal bleeding, vaginal dryness, pelvic pain, leukorrhea[Ref] Hematologic Common (1% to 10%): Anemia, leukopenia[Ref] Hepatic Common (1% to 10%): Increased gamma GT, increased SGOT, increased SGPT, increased alkaline phosphatase Uncommon (0.1% to 1%): Hepatobiliary events (e.g., increased bilirubin), hepatitis Rare (less than 0.1%): Changes in liver function (liver inflammation, liver pain, liver swelling)[Ref] Metabolic Common (1% to 10%): Weight gain, hypercholesterolemia, weight loss, anorexia Uncommon (0.1% to 1%): Hypercalcemia (with or without an increase in parathyroid hormone)[Ref] Hypersensitivity Common (1% to 10%): Allergic reactions Uncommon (0.1% to 1%): Urticaria Rare (less than 0.1%): Anaphylaxis, anaphylactoid reaction Very rare (less than 0.01%): Angioedema[Ref]

1) אין לי שום מידע על בנך כדי לענות לך 2) תבחין ACTH בודק את יכול יותרת הכיליה ליצר את הורמון הקורטיזול וגם בודק האם יש פגם בתהליך יצור הקורטיזול הגורם ליותרת הכיליה ליצר הורמונים בעלי גוון זיכרי המקדמים את גיל העצמות. אם גיל העצמות מתקדם מאוד, מבצעים אותו כדי להבין למה. אין לי נתונים כדי לדעת למה רוצים לבצע זאת אצל בנך

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