טינטון
דיון מתוך פורום אף אוזן גרון
האם ידוע לך אם צמח בשם גינקו בלובה עוזר לטינטון ?
שלום אסי הדבר נחקר וחד משמעית אין השפעה מעבר לאפקט פלצבו (כלומר היעילות זהה ליעילות של חוסר טיפול...). העתקתי לך משני מאמרים אחרונים בנושא: Ginkgo biloba does not benefit patients with tinnitus: a randomized placebo-controlled double-blind trial AND meta-analysis of randomized trials. Rejali D, Sivakumar A, Balaji N. Clin Otolaryngol Allied Sci. 2004 Jun;29(3):226-31 department of Otolaryngology, Monklands Hospital, Airdrie, UK. The objective was to ascertain if Ginkgo biloba benefits patients with tinnitus. The study design was: 1. Randomized double blind trial of Ginkgo biloba versus placebo; 2. A meta-analysis of randomized placebo controlled double blind trials. Participants included 66 adult patients with tinnitus AND six (including our study) randomized placebo controlled double blind trials were meta-analysed.The main outcome measures were the Tinnitus Handicap Inventory (THI), Glasgow Health Status Inventory (GHSI) AND average of hearing threshold at 0.5, 1, 2, 4 kHz. In the meta-analysis the proportion of patients gaining benefit AND an overall odds ratio were determined. ....In conclusion, Ginkgo biloba does not benefit patients with tinnitus. Ginkgo biloba extracts for tinnitus: More hype than hope? Smith PF, Zheng Y, Darlington CL. J Ethnopharmacol. 2005 Aug 22;100(1-2):95-9. Department of Pharmacology AND Toxicology, School of Medical Sciences, University of Otago, Dunedin, New Zealand. The investigation into the effects of Ginkgo biloba extracts on tinnitus has suffered from a dearth of effective animal models as well as systematic clinical trials employing double-blind AND placebo-controlled designs. Some clinical trials have yielded positive results, however, these studies are few AND have been limited either by design flaws, the small size of the significant effects, OR else the results have not been published in peer-reviewed journals AND therefore the quality of the research is not assured. By contrast, the two most systematic clinical trials, both double-blind AND placebo controlled, AND published in respected peer-reviewed journals, have yielded negative results AND suggest that Ginkgo biloba extracts are of little more use in the treatment of tinnitus than a placebo. Treatments for tinnitus that do not have therapeutic efficacy not only waste money but can potentially prevent patients from seeking therapy that is efficacious. Furthermore, the unsupervised use of Ginkgo biloba extracts with other medications could lead to adverse side effects which are unnecessary AND not justified in terms of therapeutic benefit בברכה ד"ר טלי מרק