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Herpes Simplex II Primary maternal infection may present as a flu-like syndrome with fever, headache, malaise, AND myalgias. Grouped painful, superficial genital ulcers are typical. Transplacental infection of the fetus is rare during pregnancy. Intrauterine HSV infection has uncommonly been associated with skin lesions, chorioretinitis, microcephaly, hydranencephaly , AND microphthalmia[1,2]. While primary HSV infections in the first trimester are associated with higher rates of spontaneous abortion AND stillbirth [3]. infection later in pregnancy appears more likely to be associated with preterm labor OR growth restriction[4]. Of greatest concern is the risk of primary infection acquired at birth which could lead to herpetic meningitis. The infection rate is nearly 50% for infants born vaginally in primary infection. The risk falls to 4% for infants born during a recurrent infection [4, 5]. Cesarean section is recommended for all women in labor with active herpes infection. אמנם כתוב שיכולה להתבצע הדבקה ברחם אבל נדיר.... האם???