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New Guidelines for Cancer Survivors American Cancer Society Updates Its Diet AND Exercise Guidelines WebMD Medical News Nov. 29, 2006 -- There are more than 10 million cancer survivors in the U.S., AND the American Cancer Society (ACS) has new diet AND exercise guidelines for them. The guidelines appear in the November/December issue of CA: A Cancer Journal for Clinicians. The ACS doesn't claim to have nailed down all the facts on nutrition AND physical activity for cancer survivors. But "reasonable conclusions can be made on several issues," write the researchers. They included Colleen Doyle, MS, RD, director of nutrition AND physical activity for the ACS. Among the recommendations: Strive for a healthy weight. If you're overweight, go for modest weight loss (up to 2 pounds weekly) with a doctor's supervision. Limit fat to 20% to 35% of calories. Keep saturated fat to less than 10% of calories AND trans fat to less than 3% of calories. Include foods rich in omega-3 fatty acids, such as fish AND walnuts. Go for lean proteins such as fish, lean meat AND poultry, nuts, seeds, eggs, low-fat dairy products, AND legumes. Include healthy carbohydrates such as vegetables, fruit, whole grains, AND legumes. Weigh alcohol's risks AND benefits. Modest drinking may be heart-healthy, but it may also raise the risk of some cancers (including breast AND colon cancer), so consult your doctor. Don't overdo vitamins. A daily multivitamin supplement that meets 100% of the Daily Value may help if you can't eat a normal diet. But talk to your doctor before taking any supplements. Make regular physical activity a goal. Ask for help, if you need it, from a physical therapist OR trainer. Get your doctor's OK first, especially if you've been inactive. Don't overdo exercise. Very high levels of exercise may increase infection risk. Keep soy intake moderate if you've had breast cancer. Up to three daily servings of soy foods, such as tofu AND soy milk, may be OK, but it may be prudent to avoid high doses of soy in soy powders AND supplements. --------------------------------------------------------------------------------

Don't overdo vitamins. A daily multivitamin supplement that meets 100% of the Daily Value may help if you can't eat a normal diet. But talk to your doctor before taking any supplements פושעים. פשע לאור היום.

INTRODUCTION — Complementary AND alternative medicine (CAM) has been defined by the National Center for Complementary AND Alternative Medicine as "a group of diverse medical AND health care systems, practices, AND products that are not presently considered to be part of conventional medicine" [1]. For some CAM practices, there is scientific evidence that a treatment is both beneficial AND safe. For many other practices, evidence is lacking OR inconclusive. Between 48 AND 88 percent of patients with cancer use some form of CAM. Most patients who use CAM are not dissatisfied with traditional medicine, but find that complementary AND alternative treatments appeal to their values AND beliefs about health AND life. Being diagnosed with cancer AND undergoing treatment can be a frightening, exhausting, AND demanding experience. CAM appeals to many patients with cancer because they hope to feel better AND decrease uncomfortable symptoms such as pain, fatigue, AND nausea. The focus of this topic is to highlight a few of the available treatments that may be beneficial, as well as to review those that are ineffective AND could potentially be dangerous. The list of complementary AND alternative medicine treatments is ever changing; the best resource for advice about complementary AND traditional therapies is the healthcare team. Placebo effect — A placebo is an inactive medication OR treatment. Well-designed studies include a placebo treatment as well as a real treatment so that the two may be compared. The placebo effect is the positive OR negative result that occurs when a patient believes they have been given a treatment, when in fact they have been given none (or a look-alike substitute). For example, a CAM treatment that claims to improve symptoms of nausea in 50 percent of patients is of little benefit if a placebo treatment also improves symptoms in 50 percent of patients. The placebo effect is not well understood, but has a strong influence on the results of any research study, whether in traditional OR complementary medicine. COMPLEMENTARY MEDICINE — Complementary medicine is a treatment, practice, OR product that is used alongside traditional medical treatment. It is not meant to replace traditional cancer treatment, but is available to alleviate side effects OR improve a patient's sense of well-being. Alternative medical systems — Alternative medical systems are healing techniques AND beliefs that have developed over time, AND include homeopathy, naturopathy, AND traditional Chinese medicine (which includes acupuncture). Acupuncture — Acupuncture involves inserting hair-thin, metal needles into the skin at specific points on the body. It causes little to no pain. Electrical stimulation is sometimes applied to the acupuncture needle. There have been numerous studies of acupuncture's efficacy in reducing nausea, pain, AND hot flashes, AND results have been mixed. • Acupuncture with electrical stimulation has been found to be useful in treating nausea AND vomiting from chemotherapy; women using acupuncture required less medication for nausea AND vomiting than women who used no acupuncture [2]. • Some trials suggest that acupuncture can reduce cancer pain, although a review of multiple trials showed it to be of no benefit. • Acupuncture with electrical stimulation may be of benefit in reducing hot flashes in men undergoing hormonal treatments for prostate cancer. Further study is needed to confirm this result. Other forms of traditional Chinese medicine, which use standard combinations of herbs OR botanicals for various illnesses, are difficult to study. Little information is available from controlled studies regarding the safety AND efficacy of this form of treatment. Homeopathy AND naturopathy — Naturopathy has not been studied in controlled, well-designed studies, AND the risks, benefits, AND efficacy have not been established. There have been several clinical studies of homeopathy, but the results were contradictory AND systematic reviews (which combine the results of multiple clinical trials) have not shown homeopathy to be of proven benefit for any medical condition. In addition, patients AND their families are not advised to spend large amounts of money on treatments that are not proven to be of benefit. Mind-body techniques — Mind-body techniques include practices such as hypnosis, guided imagery, meditation, yoga, biofeedback, AND prayer. They may be useful before OR during painful OR stress-inducing medical procedures, chemotherapy, OR radiation treatment to control anxiety, pain, OR nausea AND vomiting. Patients of any age can learn mind-body techniques. Hypnotherapy — Hypnosis is a state of altered consciousness that allows a patient to focus away from their pain, anxiety, OR nausea. Patients who are hypnotized are not sleeping, but are actually in a state of heightened imagination, similar to daydreaming. An expert can hypnotize an individual, OR a patient can learn self-hypnosis techniques. Hypnosis is safe AND has few side effects. It is not clear how OR if hypnosis is helpful, though studies have suggested that it may be useful for controlling pain AND nausea/vomiting in various settings, AND may reduce vomiting that can develop before starting chemotherapy (called anticipatory emesis). Hypnosis may also be useful in children for preventing anxiety AND pain from difficult procedures such as lumbar puncture (spinal tap) OR bone marrow biopsy. Visual OR guided imagery — Visual OR guided imagery is a technique that encourages the patient to relax by focusing on calming thoughts OR experiences. The patient sits OR lies in a comfortable position while imagining a pleasant experience such as relaxing on the beach. In one study, women receiving chemotherapy for newly diagnosed breast cancer had a better quality of life if they used relaxation training AND guided imagery, as compared to a group that had chemotherapy alone [3]. Spirituality — A majority of individuals have religious beliefs, AND many of these persons rely on their religion OR spirituality in difficult times, such as during treatments for cancer [4]. Researchers found that spirituality, when combined with conventional medicine, was an important component in the healing process AND was of benefit not only to the patient but also to caregivers AND healthcare professionals [5]. Some, but not all, studies have shown that religious involvement AND spirituality are associated with better health outcomes, including longer life, improved coping skills, better health in general, AND lower rates of anxiety, depression, AND suicide [6]. Body-based therapies — Body-based therapies use movement OR manipulation of one OR more parts of the body. Massage therapy — Massage is a body-based therapy that uses therapeutic touch, which involves stroking AND kneading the skin, muscle, AND connective tissues. There are several types of massage therapy. • Classic OR Swedish massage is massage aimed primarily at muscles. It reduces tension AND increases blood flow. • Reflexology is massage of the hands AND feet based on a system of points that correlate to other areas of the body. • Chair massage is done while the patient sits fully clothed in a special chair that slopes forward, allowing the therapist access to the back, neck, AND shoulders. • Deep tissue massage is a form of intense tissue manipulation. A study was done in 1,290 cancer patients who received massage therapy at Memorial Sloan-Kettering Cancer Center. It found that pain, anxiety, fatigue, AND nausea decreased by 50 percent in patients who received massage. Some patients reported benefits lasting up to 48 hours [7]. A small number of insurance companies cover massage therapy as a complementary cancer treatment. Energy therapies — Energy therapies involve using the body's energy fields to heal AND maintain wellness. Believers in energy medicine describe disruptions in the energy field as a cause for illness, AND teach that balancing energy can aid in healing. It is difficult to study the effectiveness of energy medicine due to the intangible nature of the body's "energy." Reiki is a form of energy medicine, AND has been evaluated in several clinical trials for treatment of anxiety AND improvement of well-being in cancer patients. Some, but not all, trials showed positive results, although the studies showing benefit were not well designed AND it is difficult to distinguish the true benefit from placebo effect. ALTERNATIVE CANCER TREATMENTS — Alternative cancer treatments (ACTs) are usually promoted as replacements to traditional cancer treatments. Cancer patients may seek them out in the hope of a cure. Some ACTs require the patient to receive treatment at their clinics, often located outside the United States. In many cases, reliable clinical trials have found these treatments ineffective OR unsafe, AND the FDA has not given approval for these treatments inside the United States. Dietary ACTs — Good nutrition is important for cancer patients. None of the ACTs are proven to prolong life OR cure cancer. In addition, some alternative cancer diet treatments are costly AND potentially harmful. Gerson regimen — The Gerson regimen requires an organic, vegetarian diet, AND includes a strict schedule for ingesting juice made from fruit AND vegetables. In addition, patients are given a number of vitamin supplements. No clinical study has proven this regimen's efficacy. It is not recommended AND may be expensive AND harmful. Macrobiotic diets — Macrobiotic diets are low-fat, vegetarian diets that include large amounts of complex carbohydrates. One report found that one-third of cancer patients who followed a macrobiotic diet lost weight, which resulted in other problems [8]. This was likely due to several factors, including the expense OR inaccessibility of some of the required foods, time spent preparing the meals, AND the restrictive, sometimes unpleasant, nature of the diet. Macrobiotic diets are not recommended for persons with cancer. Selected vegetables — Selected vegetables (SV), also called Sun's soup, is a blended, boiled, AND freeze-dried product that claims to have immune-stimulatory AND anticancer properties. Two small studies have been conducted in patients with late stage non-small cell lung cancer, both of which found that patients who received the supplement had an improved survival. Patients in both studies received traditional medical treatments as well as the SV mix. However, the studies were small AND had weaknesses in study design; further studies are needed before the treatment can be considered safe AND effective. Herbal medicine — Combinations of herbs (also called botanicals) are often promoted as ACTs. Herbal medicines may come in the form of a powder, liquid, OR pill. Examples of herbal treatments include essiac, green tea, mistletoe, PC-SPES (a mixture of herbs marketed for prostate cancer, now recalled), sho-saik-to, AND St. John's wort [9]. None of these herbals have proven to cure OR improve cancer in reliable clinical studies; some can cause dangerous side effects (show table 1). In addition, some herbal products can interact with traditional cancer treatments, making traditional treatments less effective (show table 2) [9]. Other supplements — A number of dietary supplements have been advertised as being useful ACTs. These include coenzyme Q10, hydrazine, melatonin, shark cartilage, shiitake mushroom extract, AND thymus extract. No supplement has proven reliable as either an alternative OR complement to traditional cancer treatment [9]. PATIENTS CONSIDERING CAM — Any person who is considering use of a complementary, alternative, OR traditional medical treatment should gather information about the safety, risks, AND benefits of the treatment. Reliable information sources include the healthcare team (physician, nurse, dietitian) AND government-sponsored web sites. It is important to choose the person providing CAM with care; patients should inquire about education AND licensing requirements since these vary by state. The safety of CAM treatments should be considered. Being "natural" does not mean that a product OR treatment is safe. The cost of a CAM treatment must also be considered, as these are generally not covered by commercial OR government-funded health insurance. A patient OR family who uses their life's savings for an unproven "cure" is likely to be disappointed. When evaluating an alternative OR complementary treatment, consider the following questions: • Does the treatment require patients to stop traditional medical care? • Does it claim to cure cancer? • Is it offered by only one individual OR by an established, recognized cancer treatment facility? • Is it a secret that only certain people can share? • Does it require travel to another country? Is it approved in the United States? • Is it based on well-controlled, scientific research? • Is it expensive? • Is the group OR person promoting the CAM treatment an expert in cancer treatment? • Do the promoters attack the scientific AND medical research community? WHERE TO GET MORE INFORMATION — Your healthcare provider is the best source of information for questions AND concerns related to your medical problem. Because no two patients are exactly alike AND recommendations can vary from one person to another, it is important to seek guidance from a provider who is familiar with your individual situation. This discussion will be updated as needed every four months on our web site (www.patients.uptodate.com). Additional topics as well as selected discussions written for healthcare professionals are also available for those who would like more detailed information. A number of web sites have information about medical problems AND treatments, although it can be difficult to know which sites are reputable. Information provided by the National Institutes of Health, national medical societies AND some other well-established organizations are often reliable sources of information, although the frequency with which they are updated is variable. • American Cancer Society 1-800-ACS-2345 (www.cancer.org/) • National Library of Medicine (www.nlm.nih.gov/medlineplus) • National Cancer Institute 1-800-4-CANCER (www.nci.nih.gov) • National Center for Complementary AND Alternative Medicine (nccam.nih.gov/) • Memorial Sloan-Kettering Cancer Center (www.mskcc.org) • People Living With Cancer: The official patient information website of the American Society of Clinical Oncology (www.plwc.org/portal/site/PLWC) [1-12]