תודה, פרופ' זיידמן על הקישור המעניין

ראי תשובה למטה.

עד כה פורסם דיווח אחד על קשר אפשרי בין רטינובלסטומה בילדים לאחר טיפולי IVF (על בסיס חמישה מקרים שנצפו), אך מחקרים שחזרו על המחקר לא מצאו קשר כזה. ראי: Br J Clin Pharmacol. 2004 Aug;58(2):209-11. Links In vitro fertilization AND childhood retinoblastoma.Bradbury BD, Jick H. The Boston Collaborative Drug Surveillance Program, Boston University School of Medicine, 11 Muzzey Street, Lexington, MA 02421, USA. [email protected] AIMS: To estimate the frequency of childhood retinoblastoma among children conceived by in vitro fertilization (IVF). METHODS: Using the United Kingdom-based General Practice Research Database (GPRD), we identified all live births, cases of retinoblastoma AND IVF procedures occurring between January 1989 AND December 2001. RESULTS: We identified 0 cases of retinoblastoma among 176 children conceived by IVF (Risk = 0/176, one-sided 97.5% CI 0, 0.02) AND 24 cases of retinoblastoma diagnosed before age 5 years among 358,094 children not conceived by IVF (6.7 cases per 100,000 births [95% CI 4.5, 10]). CONCLUSIONS: These data provide some reassurance that children born as a result of IVF are not at markedly increased risk of retinoblastoma. http://www.ncbi.nlm.nih.gov/pubmed/15255804?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed