IVF וסרטן ?

אין ספק שנשים שסובלות מאי פריון, במיוחד אלו שמעולם לא הרו, נמצאות בסיכון מוגבר לסרטן. לעומת זאת מחקרים רבים לא מצאו כל קשר בין טיפולי פריון וסרטן, וישנם מחקרים שמצאו קשר עם עליה קלה ביותר. בכל מקרה למעט הקפדה על מעקבים רגילים אין צורך בהתערבות מיוחדת. למשל המחקר הגדול האחרון שפורסם החודש: BMJ. 2009 Feb 5;338:b249. doi: 10.1136/bmj.b249. Links Use of fertility drugs AND risk of ovarian cancer: Danish Population Based Cohort Stud y.Jensen A, Sharif H, Frederiksen K, Kjaer SK. Danish Cancer Society, Institute of Cancer Epidemiology, Strandboulevarden 49, DK-2100, Copenhagen, Denmark. [email protected] OBJECTIVE: To examine the effects of fertility drugs on overall risk of ovarian cancer using data from a large cohort of infertile women. DESIGN: Population based cohort study. SETTING: Danish hospitals AND private fertility clinics. PARTICIPANTS: 54,362 women with infertility problems referred to all Danish fertility clinics during 1963-98. The median age at first evaluation of infertility was 30 years (range 16-55 years), AND the median age at the end of follow-up was 47 (range 18-81) years. Included in the analysis were 156 women with invasive epithelial ovarian cancer (cases) AND 1241 subcohort members identified in the cohort during follow-up in 2006. MAIN OUTCOME MEASURE: Effect of four groups of fertility drugs (gonadotrophins, clomifene citrate, human chorionic gonadotrophin, AND gonadotrophin releasing hormone) on overall risk of ovarian cancer after adjustment for potential confounding factors. RESULTS: Analyses within cohort showed no overall increased risk of ovarian cancer after any use of gonadotrophins (rate ratio 0.83, 95% confidence interval 0.50 to 1.37), clomifene (1.14, 0.79 to 1.64), human chorionic gonadotrophin (0.89, 0.62 to 1.29), OR gonadotrophin releasing hormone (0.80, 0.42 to 1.51). Furthermore, no associations were found between all four groups of fertility drugs AND number of cycles of use, length of follow-up, OR parity. CONCLUSION: No convincing association was found between use of fertility drugs AND risk of ovarian cancer. http://www.ncbi.nlm.nih.gov/pubmed/19196744?ordinalpos=13&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum