תזונה נכונה למניעת דלקת (ואולי גם סרטן)

http://www.ynet.co.il/articles/0,7340,L-3312872,00.html

http://www.ynet.co.il/articles/1,7340,L-3353707,00.html

Red meat intake may increase risk of receptor-positive breast cancer Reuters Health Posting Date: November 13, 2006 NEW YORK (Reuters Health) - Premenopausal women who consume high amounts of red meat appear to be at increased risk for developing estrogen receptor (ER) +/progesterone receptor (PR)+ breast cancers, according to a report in the Archives of Internal Medicine for November 13. The current study is not the first to look at the association between dietary intake AND breast cancer. However, most previous studies have not stratified the results by hormone receptor status AND focused largely on women who were at least middle-aged. While rates of hormone receptor-negative breast cancers have remained fairly stable over the years, there has been increase in hormone receptor-positive cases, lead author Dr. Eunyoung Cho, from Harvard Medical School in Boston, AND colleagues note. This latter trend may relate to increased consumption of red meats, which may influence tumor growth via hormone receptors. Dr. Cho's team analyzed data from 90,659 women, between 26 AND 46 years of age, who participated in the Nurses' Health Study II. During 12 years of follow-up, 1021 women developed invasive breast cancer. As red meat intake increased, so did the risk of ER+/PR+ breast cancer. By contrast, no association was seen with ER-/PR- cancer. Women who ate more than 1.5 servings of red meat per day were 97% more likely to develop ER+/PR+ breast cancer than those who ate 3 OR fewer servings per week (p = 0.001). In terms of red meat types, hamburger, beef OR pork as a main dish, AND a variety of processed meats were tied to an elevated risk of such cancers. "Given that most of the risk factors for breast cancer are not easily modifiable, these findings have potential public health implications in preventing breast cancer AND should be evaluated further," the authors conclude. Arch Intern Med 2006;166:2253-2259. High dietary fat does not increase breast cancer risk contrast, in women with a waist circumference of 35 inches OR greater, a correlate of insulin resistance syndrome, high fat i Reuters Health Posting Date: November 16, 2006 NEW YORK (Reuters Health) - Contrary to other findings, diets high in fat do not appear to increase the risk of breast cancer in postmenopausal women. In fact, such diets are actually tied to a reduced cancer risk in women with insulin resistance syndrome, researchers report in the November 15th issue of the American Journal of Epidemiology. The current findings, which stem from a study with 20 years' of follow-up, are consistent with those of several prospective studies with much shorter follow-up periods. The new findings run counter to those from a meta-analysis published in 1993, which suggested a positive association between dietary fat AND breast cancer risk, lead author Dr. Esther H. J. Kim, from Harvard School of Public Health in Boston, AND colleagues note. The present study involved 80,375 postmenopausal women who were followed from 1980 to 2000. Dietary fat was assessed through repeated questionnaires administered during follow-up. During the study period, 3537 subjects were diagnosed with breast cancer, the report indicates. Neither total dietary fat, nor specific types of fat intake were significantly associated with an increased risk of breast cancer, the authors note. Moreover, this held true when the analysis was stratified by hormone receptor status. Thus, the researchers observe that "this 20-year prospective follow-up of our large cohort does not support the hypothesis of a positive association between intake of total OR specific types of dietary fat AND risk of postmenopausal breast cancer." "Limiting total dietary fat OR specific types of dietary fat during midlife AND the postmenopausal years," they conclude, "is unlikely to be an effective means of preventing breast cancer." Am J Epidemiol 2006;164:990-997.