ארמור Armour

שלום רב; מה המקבילה של 500 מ"ג סינטרואיד בתרופה Armour לתת-פעילות בלוטת התריס? (האם אפשר לומר ש: 100 מ"ג סינטרואיד שווה ל- ארמור 60 מ"ג?) תודה מראש שרה

שלום שרה ARMOUR זה Thyroid extract (desiccated thyroid) (תכשיר שמכיל תמצית טבעית של בלוטת תריס- הורמונים T3 ו-T4). מצרפת כאן פיסקה מתוך מאגר המידע UPTODATE, שתוכלי להדפיס ולתת לרופא המטפל, שיעקוב אחר תפקוד בלוטת התריס שלך. בדרך כלל 60 מ"ג של ARMOUR- אקויוולנטי ל-100 מיקרוגרם של תכשיר שמכיל T4. Converting from desiccated thyroid extract to T4 — For patients who are taking desiccated thyroid or T4-T3 combination preparations, we prefer to switch them to T4. In general, 1 grain of desiccated thyroid extract (60 mg) contains about 38 mcg T4 and 9 mcg T3. Using a conversion of 9 mcg T3 is equivalent to about 36 mcg T4, 1 grain would be equivalent to about 74 mcg T4. However, in a randomized trial comparing T4 with desiccated thyroid extract, 1 grain (60 mg) of extract was equivalent to 88 mcg of T4 [50]. Both of these conversions result in lower amounts of T4 than traditionally recommended; the US Pharmacopoeia Drug Information suggests 1 grain (60 mg) is equivalent to 100 mcg [50]. Thus, many clinicians use a simple conversion factor of 1 grain = 100 mcg T4. For a patient who is taking 1½ grains (90 mg) of desiccated thyroid, an equivalent T4 dose ranges from 112 to 150 mcg. Some clinicians prefer to begin with the higher dose (150 mcg) and slowly taper the dose if the TSH measured six weeks after switching remains below the reference range. For patients taking T4-T3 combination preparations, the equivalent dose of T4 can be calculated based upon the amount of T4 and T3 in the preparation. As an example, for a patient who is taking a preparation of 12.5 mcg T3 combined with 50 mcg T4, the equivalent dose of T4 is approximately 100 mcg (50 mcg T4 plus four times the dose of T3). Often, patients who are doing well symptomatically on a combination preparation (eg, Armour thyroid) refuse to be switched to T4. As long as their thyroid function tests are normal and are monitored periodically, it is probably safe for them to continue to take the thyroid preparation they prefer. Also, Armour thyroid is cheaper than most branded T4 products.